Pushtiie Shakti has appeared in the second season of a famous comedy soap that ran on Zee TV known as Hum Paanch, in the late 1990s. She played the youngest daughter of Anand Mathur (played by Ashok Saraf), "Chotti" among the five daughters. This serial was produced by Ekta Kapoor. Actor Vidya Balan happened to play one of the elder sisters of Pushtiie in this soap.
Pushtiie played a role in Jassi Jaisi Koi Nahin, the Indian version of Ugly Betty.She played the character of Sanya's best friend in the soap Sanya that was aired on Hungama TV.
Her brother Vrajesh Hirjee, happens to be a famous comedian and actor in Bollywood films and shows.