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Vinod Scaria is a Scientist at the GN Ramachandran Knowledge Center for Genome Informatics at the Institute of Genomics and Integrative Biology, Delhi ,India His major research interests include Computational Biology of noncoding RNA and their relevance in Host-Pathogen interactions. He has published a number of papers in peer reviewed publications.

Education

He had his schooling from the Silver Hills High School in 1996 and obtained his Pre-University diploma from the University of Calicut in 1998. He finished his bachelor's degree in medicine and Surgery from the Calicut Medical College, University of Calicut in 2004

Career

In IGIB (2004-present)

Discovered the role of human microRNAs as a potential antiviral mechanism against Human Immunodeficiency Virus (HIV) and suggested the molecular mechanism of the role of microRNAs as a critical determinant of long-term non-progression (LTNP) states. Also suggested microRNA level variation to have prognostic value (Biochem Biophys Res Commun. 2005).This work has been extensively cited in top journals including a news and views article in Nature Reviews Drug Discovery.

Suggested a comprehensive model for microRNA mediated host-virus interaction and suggested design and use of artificial microRNAs as a therapeutic (Retrovirology 2006).


In Medical School(1998-2004)

Has been one of the pioneers of Open Access movement in India, and has been an invited contributor to Open Access News. Developed one of the first and largest databases of Medical Libraries on the Internet (MedLib) while in medical school. This has been extensively acknowledged including British Medical Journal

Pioneered E-Health and E-Health ethics research in India and pioneered one of the first studies on Cyber-pharmacies and public access of health information. Also played major role in establishing one of the first E-Health groups in the country while in medical school. The group later evolved into a full fledged Telemedicine and E-Health facility at Calicut Medical College. Papers published have been cited in top Journals in the field. Of his papers, 5 of them have over 100 citations a shown by google Scholar. [1]

He is a peer reviewer, editorial board member, advisor of various National and International journals including PLoS journals , Bioinformatics(Oxford) and Frontiers in Biosciences. He is also the founding Editorial board member of Calicut Medical Journal. He has been instrumental in creating a number of popular research tools online and are available at [RNA@IGIB].


References

Publications

Meli R, Prasad A, Patowary A, Lalwani MK, Maini MK, Sharma M, Singh AR, Kumar G, Jadhav V, Scaria V, Sivasubbu S. FishMap: A community resource for Zebrafish genomics. Zebrafish June 2008 (In press) Cover Article


Arora A , Dutkiewicz M, Scaria V , Hariharan M, Maiti S , Kurreck J. Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif RNA (2008 accepted)

Indian Genome Variation Consortium* Genetic Landscape of the People of India: a Canvas for Disease Gene Exploration J Genetics 2008 (accepted)

Scaria V, Jadhav V. microRNAs in viral oncogenesis. Retrovirology. 2007 Nov 24;4(1):82

Scaria V, Hariharan M, Pillai B, Maiti S, Brahmachari SK. Host-virus genome interactions: macro roles for microRNAs. Cell Microbiol. 2007 Nov 6;9(12):2784-2794.

Scaria V, Hariharan M, Pillai B, Maiti S, Brahmachari SK. microRNA: an Emerging Therapeutic ChemMedChem 2007 (in press)

The NMITLI-BioSuite Team* BioSuite: A comprehensive bioinformatics software package (A unique industry–academia collaboration) Current Science. 2007 Jan 92(1): 29-38

Scaria V, Hariharan M, Maiti S, Pillai B, Brahmachari SK. Host-Virus interaction: A new role for microRNAs Retrovirology 2006 3:68 (11 October 2006)

Harish N, Gupta R, Agarwal P, Scaria V, Pillai B. DyNAVacS: an integrative tool for optimized DNA vaccine design. Nucleic Acids Research. 2006 Jul 1;34:W264-6.

Scaria V, Hariharan M, Arora A, Maiti S. Quadfinder: server for identification and analysis of quadruplex-forming motifs in nucleotide sequences. Nucleic Acids Research. 2006 Jul 1;34:W683-5.

Hariharan M, Scaria V, Pillai B, Brahmachari SK Targets for human encoded microRNAs in HIV genes. Biochem Biophys Res Commun. 2005 Dec 2;337(4):1214-8.

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