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Vivecon

Vivecon (edit|talk|history|links|watch|logs) – (View log • Stats)
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Only ref is broken, no WP:MEDRS sources found, not even a chemical structure. Seems to be discontinued. ἀνυπόδητος (talk) 10:52, 10 June 2012 (UTC)

  • keep. Research into this drug appears to be ongoing; mentioned in three papers published this year available at [1], as well as several from 2010 and 2011. JulesH (talk) 15:28, 10 June 2012 (UTC)
  • keep. Actively researched compound, multiple reputable sources discuss, this article should be expanded, not deleted. Bryan Hopping T 15:34, 10 June 2012 (UTC)
    • comment Bryan, thanks for adding refs to the mechanism section -- but the reliable ones (i.e. all but the one from the Myriad homepage) seem to mention neither "vivecon" nor "MPC-9055". Did I overlook something? --ἀνυπόδητος (talk) 07:33, 11 June 2012 (UTC)
  • delete. There is no evidence that this is an actively researched compound. Searching ClinicalTrials.gov for Myriad reveals that Myriad currently has no HIV maturation inhibitors in clinical trials. Searching the Myriad Genetics web site for vivecon or MPC-9055 (the research code for Vivecon) yields no hits. The google scholar citations are to patent applications by competitor companies who only are listing Vivecon as prior art and are not developing the compound themselves. If the chemical structure of the compound were disclosed by Myriad Genetics, then I would be opposed to deletion. But Myriad Genetics has disclosed so little information about the compound, there is no point in keeping the article. Boghog (talk) 20:11, 10 June 2012 (UTC)
This announcement seem very relevant: Myriad Genetics Suspends Its HIV Maturation Inhibitor Program Bevirimat is a different maturation inhibitor, but it appears that Myriad Genetics shut down their entire maturation inhibitor research program in favor of oncology drugs. Boghog (talk) 20:20, 10 June 2012 (UTC)
Even if research into the compound were suspended, the article would still be noteworthy. Commercially-unsuccessful research is just as noteworthy as research that leads to commercialized products.Bryan Hopping T 20:56, 10 June 2012 (UTC)
According to this Myriad Genetics 8K filing, Vivecon (MPC-9055) was a clinical backup compound to Bevirimat (MPC-4326) and the two compounds work through similar mechanisms. Bevirimat has also been discontinued, but in contrast to Vivecon, a substantial amount of data has been published on Bevirimat in reliable sources. I agree with you that even failed drugs are noteworthy but they must also be backed up by reliable sources. Bevirimat passes this second test while Vivecon does not. (note: this meeting poster gives more detail on Vivecon, but it has not been published in a peer review journal and therefore cannot be considered a reliable source). Boghog (talk) 15:46, 11 June 2012 (UTC)
Note: This debate has been included in the list of Medicine-related deletion discussions. • Gene93k (talk) 01:12, 11 June 2012 (UTC)

Relisted to generate a more thorough discussion so a clearer consensus may be reached.
Please add new comments below this notice. Thanks, Ron Ritzman (talk) 01:36, 17 June 2012 (UTC)

  • comment. As stated above, Vivecon is a discontinued drug candidate whose chemical structure has not been disclosed. Furthermore very little data has been published about the drug in reliable sources. Failed drugs can be noteworthy, but only if they continued to be used as research tools or enough information has been disclosed about them to indicate why they have been discontinued. Neither applies to Vivecon. Boghog (talk) 07:24, 17 June 2012 (UTC)
There is never any reason to vote twice. Anarchangel (talk) 03:26, 19 June 2012 (UTC)
Changed above heading from "delete" to "comment". Because the discussion had become somewhat convoluted, I merely wanted to restate the argument more clearly and succinctly. Boghog (talk) 04:43, 19 June 2012 (UTC)
This article uses material from the Wikipedia article Articles for deletion/Vivecon, that was deleted or is being discussed for deletion, which is released under the Creative Commons Attribution-ShareAlike 3.0 Unported License.
Author(s): Boghog Search for "Articles for deletion/Vivecon" on Google
View Wikipedia's deletion log of "Articles for deletion/Vivecon"
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