Lutz is a daughter of a Japanese mother, Mona Lutz and a German father, Walter E. Lutz. Her sister is model Tina Chow. Lutz was married to David Byrne. Together they have a daughter, Malu Valentine, born in 1989. Lutz and Byrne divorced in 2004.
In 1995, Lutz portrayed Nobel Peace Prize Winner, Aung San Suu Kyi, in John Boorman's film Beyond Rangoon. Lutz was cast as one of the Deetz's dinner party guests in Tim Burton's 1988 film Beetlejuice. She had a small and unseen cameo in Jonathan Demme's The Silence of the Lambs as a news reporter on TV.
Lutz had role as the main character's best in Wim Wenders' Until the End of the World, and supporting roles in Oliver Stone's Wall Street (1987) and Something Wild (1986). She played the role of Mari in the film Dead Funny (1994) an independent, drama.
Lutz designed costumes for stage performances like Punch and Judy Get Divorced (1996) from the American Repertory Theater.
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